Thermo Fisher Scientific TYMP Monoclonal Antibody (UMAB90), UltraMAB
TYMP 단백질을 인식하는 마우스 단클론 항체(UMAB90)로, Western blot 및 IHC(P) 실험에 적합합니다. 인간 시료 반응성, 정제된 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB90 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–482 of human TYMP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | –20 °C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
- For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
A platelet-derived endothelial growth factor (PD-ECGF), also known as thymidine phosphorylase (TP) or gliostatin.
In the presence of inorganic orthophosphate, it catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate.
It is chemotactic and mitogenic for endothelial cells and acts as a non-heparin-binding angiogenic factor present in platelets.
Additionally, it participates in the transformation of fluoropyrimidines, cytotoxic agents used in cancer treatment, into active cytotoxic metabolites.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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