Thermo Fisher Scientific Ubiquitin Polyclonal Antibody

Applications

Immunohistochemistry (IHC)

• Tested Dilution: 1:100–1:500

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat, D. melanogaster, Zebrafish, X. laevis, X. tropicalis, Chicken, Sheep, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, and Pig

Target Information

Ubiquitin is a highly conserved protein that plays a major role in targeting cellular proteins for degradation by the 26S proteasome. It is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. The gene encodes a fusion protein with ubiquitin at the N-terminus and ribosomal protein S27a at the C-terminus. When expressed in yeast, the protein is processed post-translationally to generate free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is part of the 40S ribosomal subunit, contains C4-type zinc finger domains, and is located in the cytoplasm. Pseudogenes derived from this gene are also present in the genome. Other ribosomal proteins, such as L40 and S30, are synthesized as fusion proteins with ubiquitin or ubiquitin-like proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.