Thermo Fisher Scientific PRKD3 Monoclonal Antibody (OTI4G6)
PRKD3 단백질을 표적하는 Mouse IgG1 단일클론 항체로 Western Blot과 IHC(Paraffin)에 적합. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도, 안정적 PBS/BSA/glycerol 버퍼 구성. 연구용으로 인간 시료 반응성 확인됨.
- 카탈로그번호
- MA526756
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 300–508 of PRKD3 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723512 |
Target Information
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phospholipase C gamma and the involvement of other PKC family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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