Thermo Fisher Scientific Phospho-IFNAR1 (Ser535, Ser538) Polyclonal Antibody
Phospho-IFNAR1 (Ser535, Ser538) 폴리클로날 항체로, 사람·마우스·랫트 반응성. IHC, ICC/IF, Flow, ELISA 등 다양한 응용 가능. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human IFNAR1 around phosphorylation sites Ser535 and Ser538 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interferons are widely used therapeutic agents due to their antitumor and antiviral effects, as well as their modulatory effects on the immune system (Biron, 2001; Kirkwood, 2002). These cytokines exert their effects by binding to the Type I Interferon Receptor (IFNAR1). Down-regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling, which is thought to be influenced by phosphorylation of Serine 535 and 539 in IFNAR1 (Kumar et al., 2003).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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