Thermo Fisher Scientific FAM3B Polyclonal Antibody
Human FAM3B 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 액상 형태로 제공되며 4°C 또는 -20°C에서 안정적 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAM3B (Product #RP-90535) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641402 |
Product Specific Information
Immunogen sequence:
TPCPSDTYAY RLLSGGGRSK YAKICFEDNL LMGEQLGNVA RGINIAIVNY VTGNVTATRC FDMYEGDNSG PMTKFIQSAA PKSLLFMVTY DDGSTRLNND AKNAIEALGS KEIRN
Highest antigen sequence identity to the following orthologs:
- Mouse: 77%
- Rat: 75%
Target Information
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures.
It is highly expressed in the pancreas and at lower levels in kidney, colon, testis, prostate, and small intestine.
FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit insulin secretion from beta-cells, playing a role in pancreatic activity.
Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species.
Three isoforms (A, B, and C) exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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