Thermo Fisher Scientific UNC13B Polyclonal Antibody
UNC13B 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체로, 인간 시료에 반응합니다. Western blot 및 IHC(파라핀) 실험에 적합하며, 액상 형태로 제공됩니다. 신경전달 관련 소포 성숙 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence PLRDVAAKGSC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933256 |
Product Specific Information
- This antibody is expected to recognize all reported isoforms (NP_074053.1; NP_001036044.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway.
It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of the readily releasable vesicle pool (RRP).
Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-142610_UNC13B_Q9Z1N9-1_Goat.svg, PA5-142610_UNC13B_Q9Z1N9-1_Goat_PDP.jpeg)
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