Thermo Fisher Scientific p38 MAPK beta Polyclonal Antibody
Rabbit polyclonal antibody targeting human p38 MAPK beta. Validated for ICC/IF applications. High specificity with 97% sequence identity to mouse and rat. Supplied in liquid form, affinity purified, and suitable for research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence, range 315–346. Recombinant protein control fragment (Product #RP-109916). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092023 |
Product Specific Information
- Immunogen sequence: EDEPEAEPYD ESVEAKERTL EEWKELTYQE VL
- Antigen sequence identity: Mouse 97%; Rat 97%
Target Information
MAPK11 (p38 beta) is a serine/threonine kinase involved in various cellular processes and is activated by proinflammatory cytokines and environmental stress. The protein encoded by p38 MAPK beta belongs to the MAP kinase family, which acts as an integration point for multiple biochemical signals. It participates in processes such as proliferation, differentiation, transcription regulation, and development. This kinase is closely related to p38 MAP kinase and can be activated by cytokines and stress via phosphorylation by MAP kinase kinases (MKKs), particularly MKK6. Transcription factor ATF2/CREB2 is a known substrate of this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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