Thermo Fisher Scientific Desmoglein 2 Polyclonal Antibody
Thermo Fisher Scientific의 Desmoglein 2 Polyclonal Antibody는 마우스에서 반응하는 rabbit IgG 항체로, Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of mouse Desmoglein 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2690322 |
Product Specific Information
This target displays homology in the following species:
- Cow: 93%
- Dog: 92%
- Guinea Pig: 100%
- Horse: 92%
- Human: 100%
- Mouse: 93%
- Rabbit: 85%
- Rat: 100%
Synthetic peptide region:
TDADEVGSDN WLANFTFASG NEGGYFHIET DTQTNEGIVT LVKEVDYEEM
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Three desmoglein subfamily members have been identified, all belonging to the cadherin cell adhesion molecule superfamily. These genes are clustered on chromosome 18. Desmoglein 2 has been identified as the autoantigen in pemphigus vulgaris, an autoimmune skin blistering disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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