Thermo Fisher Scientific DCT Polyclonal Antibody
Thermo Fisher Scientific의 DCT Polyclonal Antibody는 Mouse 및 Zebrafish에 반응하며, Western Blot, IHC, ICC/IF에 사용 가능. Rabbit IgG 기반의 비결합 액상 항체로, 고순도 친화 크로마토그래피로 정제됨. 연구용으로 멜라닌 생합성 관련 단백질 분석에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1.0 µg/mL |
| Immunohistochemistry (IHC) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of mouse DCT (aa 161–210) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688598 |
Product Specific Information
This target displays 100% homology in the following species: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish.
Target Information
The TYR-related proteins, TRP1 and TRP2, are specifically expressed in melanocytes and contribute to melanin synthesis within melanosomes. These TRPs share a similar transmembrane region, contain two metal-binding regions and a cysteine-rich EGF motif, and are localized in the melanosomal membrane. Each protein exhibits distinct catalytic activity and collectively contributes to melanin biopolymer biosynthesis. TRPs are believed to form a multi-enzyme complex, stabilizing TYR expression in melanocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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