Thermo Fisher Scientific IL17RB Polyclonal Antibody
IL17RB 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ELISA, IP 등에 사용 가능. Human, Mouse, Rat 반응성. 합성 펩타이드(aa 300-400)로부터 제작되었으며, Affinity Chromatography로 정제됨. -20°C 보관.
- 카탈로그번호
- IL17RB-201AP
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 300–400 on IL17RB protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
A number of cytokines in the interleukin (IL)-17 family, including IL-17B, IL-17C, and IL-17E, have been identified. IL-17 is a potent proinflammatory cytokine involved in diseases such as rheumatoid arthritis, multiple sclerosis, and tumor growth. IL-17B, C, and E can induce proinflammatory responses but do not bind to the IL-17 receptor, suggesting the existence of additional IL-17R-related receptors. Receptors for IL-17B and IL-17E have been identified as EV127 (mouse) and IL-17Rh1 (human), respectively. IL-17E activates the NF-κB pathway and induces IL-8 production. IL-17Rh1 mRNA is highly expressed in kidney and liver, with moderate expression in small intestine, colon, and brain.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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