Thermo Fisher Scientific MAPK11 Monoclonal Antibody (OTI1C2), TrueMAB
인간 MAPK11(p38 beta)을 표적으로 하는 Mouse IgG1 단일클론 항체. Western blot과 Immunocytochemistry에 사용 가능. 고순도 친화 크로마토그래피 정제, 무보존제 PBS 버퍼에 동결건조 형태로 제공. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C2 |
| Immunogen | Full length human recombinant protein of human MAPK11 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MAPK11 (p38 beta) is a serine/threonine kinase involved in various cellular processes, activated by proinflammatory cytokines and environmental stress.
It is part of the MAP kinase family, integrating multiple biochemical signals and regulating proliferation, differentiation, transcription, and development.
This kinase is closely related to p38 MAP kinase and is activated through phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6.
Transcription factor ATF2/CREB2 is a known substrate of this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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