Thermo Fisher Scientific IL-4 Recombinant Rabbit Monoclonal Antibody (5D8)
IL-4 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, IHC(P) 및 ELISA에 적합합니다. 높은 특이성과 재현성을 제공하며, 인간 시료에서 검증되었습니다. 액상 형태로 제공되며, -20°C 이하에서 안정적으로 보관 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5D8 |
| Immunogen | A synthesized peptide derived from human IL4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092790 |
Target Information
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells and serves as a ligand for the interleukin 4 receptor. IL-4 exhibits a broad range of biological actions. The interleukin 4 receptor also binds to IL13, contributing to overlapping functions between IL-4 and IL13. STAT6, a signal transducer and activator of transcription, plays a key role in mediating IL-4’s immune regulatory signaling. The IL-4 gene, along with IL-3, IL-5, IL-13, and CSF2, forms a cytokine gene cluster on chromosome 5q. IL-4 is located near IL13, and these genes are co-regulated by several long-range regulatory elements over approximately 120 kilobases. IL-4 delta 2 is a known splice variant of IL-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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