Thermo Fisher Scientific FEM1A Polyclonal Antibody
FEM1A 단백질을 인식하는 Thermo Fisher Scientific의 염소 다클론 항체. Western blot에 최적화되어 있으며 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태, 4°C 단기 보관 및 -20°C 장기 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues H I P E K L E T F V S L H R of human FEM1A (aa 604–617) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2102635 |
Product Specific Information
- Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX10911-PEP).
- PA1-24858 is expected to cross-react with mouse Fem1C (100% conserved) due to sequence homology.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
FEM1A (FEM-1 homolog a), also known as EPRAP (Prostaglandin E receptor 4-associated protein), is a 669 amino acid cytoplasmic protein belonging to the FEM-1 family.
FEM1A is present in atheromata and macrophages derived from peripheral blood monocytes. It may be part of an E3 ubiquitin-protein ligase complex and function as a substrate recognition subunit. FEM1A is suggested to participate in anti-inflammatory signaling of macrophages via interaction with EP4.
It is down-regulated in Rhabdomyosarcoma and considered a candidate gene for polycystic ovary syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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