
Thermo Fisher Scientific PTGES3 Monoclonal Antibody (OTI2F2), TrueMAB
인간 PTGES3 단백질을 인식하는 단클론 항체로 Western blot에 최적화됨. Mouse IgG1 아이소타입이며, 동결건조 형태로 제공. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
- 카탈로그번호
- CF803290
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F2 |
| Immunogen | Full length human recombinant protein of human PTGES3 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Steroid receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to DNA sequences upon hormone activation.
Before activation, steroid receptors associate with proteins such as HSP70, HSP90, and immunophilins (FKBP52, FKBP54, CyP-40), as well as p23, p60, and p48.
p23 forms part of a transient intermediate complex with HSP70, HSP90, and progesterone receptor (PR).
Human p23 is a 160-amino-acid phosphoprotein, highly conserved among species, and contains multiple phosphorylation sites.
It binds to HSP90 and is essential for HSP90–CyP-40 interaction with PR, playing a key role in PR function.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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