Thermo Fisher Scientific NRG2 (extracellular) Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Reconstitution: 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW), depending on sample size.
• Ships as a lyophilized powder at room temperature.
• Upon arrival, store at -20°C.
• Reconstituted solution can be stored at 4°C for up to 1 week.
• For longer storage, aliquot and keep at -20°C.
• Avoid multiple freeze/thaw cycles.
• Centrifuge antibody preparations before use (10,000 × g, 5 min).

Target Information

Neuregulin 2 (NRG2) is a member of the neuregulin family of growth and differentiation factors. Through interaction with ErbB family receptors, NRG2 promotes growth and differentiation of epithelial, neuronal, glial, and other cell types. The gene consists of 12 exons and shares structural similarity with neuregulin 1 (NRG1). NRG1 and NRG2 mediate distinct biological processes by acting at different sites and eliciting different cellular responses. The gene is located near the region associated with demyelinating Charcot–Marie–Tooth disease but is not responsible for the disorder. Alternative transcripts encoding distinct isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.