Thermo Fisher Scientific STK11 Monoclonal Antibody (OTI4B2), TrueMAB
인간 STK11(LKB1) 단백질을 인식하는 마우스 단클론 항체. Western blot에 최적화되어 있으며, 1:2,000 희석 사용 권장. 1 mg/mL 농도의 액상 형태로, PBS/BSA/glycerol buffer에 보관. 종양 억제 단백질 연구에 적합.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–236 of human STK11 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11) is a tumor suppressor belonging to the serine/threonine kinase family. It physically associates with p53 and regulates specific p53-dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. It functions as a master upstream protein kinase, regulating AMPK-related kinases as well as AMPK. Mutations in the LKB1 gene are associated with Peutz-Jeghers syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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