Thermo Fisher Scientific Factor XII Light Chain Monoclonal Antibody (C6B7)
인간 Factor XII Light Chain을 인식하는 마우스 단일클론 항체입니다. ELISA 등 연구용으로 사용되며, Protein A 정제 및 PBS(pH 7.4) 버퍼에 보존됩니다. 보존제 무첨가, -20°C에서 보관하며 동결/해동 반복을 피해야 합니다.
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Thermo Fisher Scientific Factor XII Light Chain Monoclonal Antibody (C6B7)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C6B7 |
| Immunogen | Purified human Factor XII |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes coagulation factor XII, which circulates in blood as a zymogen. Upon activation, it is converted to a two-chain serine protease with a heavy chain (alpha-factor XIIa) and a light chain. The heavy chain includes fibronectin-type domains, EGF-like domains, a kringle domain, and a proline-rich domain, while the light chain contains the catalytic domain. Factor XIIa initiates blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene prolong whole-blood clotting time but do not cause clinical symptoms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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