Thermo Fisher Scientific Nortriptyline Polyclonal Antibody

Applications

Tested Dilution

Publications

ELISA (ELISA)

5-10 µg/mL

-

Product Specifications

Species Reactivity

Chemical

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Nortriptyline-BTG

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

purified

Storage buffer

PBS, pH 7.1

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1090564

Product Specific Information

Working Concentration: 5 µg/mL. Sensitivity: 10 ng/mL Nortriptyline produces 45% inhibition in a competitive ELISA employing Tricyclic Antidepressants (TCA) (4) polyclonal antibody.

Target Information

Nortriptyline Base is a tricyclic antidepressant agent used for short-term treatment of various forms of depression. Nortriptyline blocks the norepinephrine presynaptic receptors, thereby blocking the reuptake of this neurotransmitter and raising the concentration in the synaptic cleft in the CNS. Nortriptyline also binds to alpha-adrenergic, histaminergic and cholinergic receptors. Long-term treatment with nortriptyline produces a downregulation of adrenergic receptors due to the increased stimulation of these receptors. [National Center for Biotechnology Information. PubChem Compound Database; CID=4543].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.