Thermo Fisher Scientific RuvBL2 Polyclonal Antibody
RuvBL2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, IP 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 인간 및 마우스 반응성. 연구용으로만 사용 가능.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Recommended Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 5–15 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of Human RuvB-like 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC (FFPE sections), epitope retrieval with citrate buffer (pH 6.0) is recommended
- Based on 100% sequence identity, antibody is predicted to react with Bovine
Target Information
RUVBL2 possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (5′ to 3′) activity. It is a component of the NuA4 histone acetyltransferase complex involved in transcriptional activation of select genes through histone acetylation (H4 and H2A). This modification alters nucleosome–DNA interactions and promotes recruitment of transcription-regulating proteins. The NuA4 complex is implicated in oncogene- and proto-oncogene-mediated growth induction, tumor suppressor-mediated growth arrest, replicative senescence, apoptosis, and DNA repair. RUVBL2, together with RUVBL1 and EP400, contributes to the ATPase and helicase activities of NuA4 and plays a direct role in DNA repair. It is essential for MYC-mediated oncogenic transformation and modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex. RUVBL2 may also inhibit the transcriptional activity of ATF2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific MCEF Polyclonal Antibody
194,600원
Thermo Fisher Scientific
Thermo Fisher Scientific RuvBL2 Polyclonal Antibody
194,600원
Thermo Fisher Scientific
Thermo Fisher Scientific RuvBL2 Polyclonal Antibody
658,900원
Thermo Fisher Scientific
Thermo Fisher Scientific RuvBL2 Polyclonal Antibody
194,600원
Thermo Fisher Scientific
Thermo Fisher Scientific Vinculin Polyclonal Antibody
194,600원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|