Thermo Fisher Scientific alpha Galactosidase Polyclonal Antibody
Thermo Fisher Scientific의 alpha Galactosidase Polyclonal Antibody는 인간 및 랫트 반응성을 가지며, WB, IHC, ICC 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제된 비결합형 액상 항체로, Fabry 질환 연구 등 효소 분석에 활용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 7 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Immunoprecipitation (IP) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Human, Pig |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 1–289 of Human Galactosidase alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.157 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544825 |
Product Specific Information
- Recommended positive controls: 293T, HeLa, Rat Lung
- Predicted reactivity: Rat (82%), Pig (84%), Bovine (80%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. The enzyme predominantly hydrolyzes ceramide trihexoside and can catalyze the hydrolysis of melibiose into galactose and glucose. Mutations in this gene lead to Fabry disease, a rare lysosomal storage disorder caused by failure to catabolize alpha-D-galactosyl glycolipid moieties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-27349_alpha_Galactosidase_P06280-1_Rabbit.svg
- PA5-27349_alpha_Galactosidase_P06280-1_Rabbit_PDP.jpeg
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