Thermo Fisher Scientific BIN1 Polyclonal Antibody
BIN1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체로, Western blot에 적합합니다. 인간에 반응하며, 다른 종에서도 예측 반응성을 보입니다. 액상 형태로 공급되며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (SDNAPAKGNKSPS) corresponding to the internal amino acids of BIN1 (aa 286–299). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10989598 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1,000.
Target Information
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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