Thermo Fisher Scientific ZFP36 Monoclonal Antibody (OTI3D10)
ZFP36 단백질을 인식하는 Thermo Fisher monoclonal antibody로, WB, IHC(F), ICC/IF, Flow Cytometry 등에 사용 가능. Human 및 Mouse 반응성. Affinity Chromatography로 정제된 액상 항체이며, PBS/BSA/glycerol buffer에 보관. 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | 1:50–1:150 | - |
| Flow Cytometry (Flow) | 1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D10 |
| Immunogen | Full length human recombinant protein of ZFP36 produced in HEK293T cell (Target Family: ZFP36, UniProt ID: P26651-1, Antigen Range: 1–326, Antigen Length: 326) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725703 |
Target Information
ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increases macrophage gene mRNAs and inflammatory TNF protein release, while overexpression decreases these levels, supporting its role in macrophage gene regulation. ZFP36 can be phosphorylated by JNK and other MAP kinases. It is implicated in prostate cancer prognosis and rheumatoid arthritis disease activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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