Thermo Fisher Scientific RAB11FIP1 Polyclonal Antibody
RAB11FIP1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF에 적합합니다. 인간 및 생쥐 시료 반응성이 있으며, PBS와 글리세롤 기반 용액 형태로 제공됩니다. Affinity chromatography로 정제되어 높은 특이성과 재현성을 제공합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RAB11FIP1 (Accession Q6WKZ4), corresponding to amino acid residues F148–P198 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900448 |
Product Specific Information
This antibody detects endogenous levels of total RAB11FIP1.
Target Information
Rab11-FIP1 (Rab 11 family-interacting protein 1), also known as Rab-coupling protein (RCP), is a 1283 amino acid Rab 11 effector protein. By interacting with Rab GTPases, it participates in the endosomal recycling process and may regulate membrane trafficking along the phagocytic pathway and during phagocytosis.
Localized to the recycling endosome, cytoplasmic membrane, and phagosome membranes, Rab11-FIP1 is expressed as five isoforms produced by alternative splicing. Isoform two, the most highly expressed, is found in brain, lung, testis, small intestine, spleen, and heart. It can form a homooligomer and interacts with Rab 4A, Rab 11A, Rab 11B, and Rab 25.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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