Thermo Fisher Scientific TRIP13 Monoclonal Antibody (OTI2F5), TrueMAB
TRIP13 단백질을 인식하는 마우스 단클론 항체로, Western blot과 IHC(P) 분석에 적합합니다. 인간 TRIP13 아미노산 31-148을 항원으로 제작되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 31–148 of human TRIP13 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner. TRIP13 (thyroid hormone receptor interactor 13), also called 16E1BP, interacts with the ligand binding domain of the thyroid receptor (TR) and various target genes, including human papilloma virus type 16 (HPV16) E1. Unlike most TRIP proteins, TRIP13 does not require thyroid hormone to interact with TR. The association of TRIP13 with HPV16 E1 suggests a potential tumor suppressor gene function. TRIP13 is a 432-amino-acid protein with two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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