Thermo Fisher Scientific Oncostatin M Monoclonal Antibody (17001.31)
인간 Oncostatin M을 인식하는 Mouse IgG2a 단일클론 항체로, WB, ELISA, 중화 실험에 적합합니다. 정제된 액상 형태로 제공되며, PBS 및 trehalose buffer에 보존됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA124832
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| ELISA (ELISA) | 0.5–1 µg/mL |
| Neutralization (Neu) | 0.1–5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 17001.31 |
| Immunogen | Recombinant full-length human Oncostatin M protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_795072 |
Product Specific Information
- MA1-24832 does not react with mouse.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Oncostatin M (OSM) is a growth and differentiation factor involved in the regulation of neurogenesis, osteogenesis, and hematopoiesis. Produced by activated T cells, monocytes, and Kaposi’s sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells, and Kaposi’s sarcoma cells, but inhibits the growth of certain normal and tumor cell lines. OSM also promotes cytokine release (e.g., IL-6, GM-CSF, G-CSF) from endothelial cells and enhances LDL receptor expression in hepatoma cells. It shares structural and functional similarities with LIF, IL-6, and CNTF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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