Thermo Fisher Scientific PCCB Polyclonal Antibody
Human PCCB 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 Immunohistochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 저장용액에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PCCB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645247 |
Product Specific Information
Immunogen sequence:
SSKHLCGDTN YAWPTAEIAV MGAKGAVEII FKGHENVEAA QAEYIEKFAN PFPAAVRGFV DDIIQPSSTR ARICCDLDVL
Highest antigen sequence identity to orthologs:
- Mouse: 94%
- Rat: 94%
Target Information
The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that likely acts as a dodecamer composed of six alpha and six beta subunits. This gene encodes the beta subunit of PCC.
Defects in this gene are associated with propionic acidemia type II (PA-2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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