Thermo Fisher Scientific NFKBIL2 Polyclonal Antibody
Human NFKBIL2 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 고순도와 재현성 제공. NF-κB 매개 전사 조절 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NFKBIL2. Recombinant protein control fragment (Product #RP-89378). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644646 |
Product Specific Information
Immunogen sequence:
WNRRNDMGET LLHRACIEGQ LRRVQDLVRQ GHPLNPRDYC GWTPLHEACN YGHLEIVRFL LDHGAAVDDP GGQGCEGITP LHDALNCGHF EVAELLLERG ASVTLRTRK
Highest antigen sequence identity to the following orthologs:
- Mouse: 97%
- Rat: 97%
Target Information
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. It may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, freeing the NF-kappa-B complexes to enter the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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