Thermo Fisher Scientific Phospho-JMJD2B (Thr305) Polyclonal Antibody
JMJD2B 단백질의 Thr305 인산화 부위를 특이적으로 인식하는 폴리클로날 항체로, Human, Mouse, Rat에 반응합니다. WB, IHC, ICC, ELISA 등 다양한 응용에 적합하며, 고순도 Protein A 정제 및 안정적인 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human JMJD2B around the phosphorylation site of Thr305 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a role in the histone code.
Does not demethylate histone H3 Lys-4, H3 Lys-27, H3 Lys-36, nor H4 Lys-20.
Only able to demethylate trimethylated H3 Lys-9, with a weaker activity than KDM4A, KDM4C, and KDM4D.
Demethylation of Lys residue generates formaldehyde and succinate.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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