Thermo Fisher Scientific NALP1 Polyclonal Antibody
인간 NLRP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합하며, 고순도 Affinity chromatography로 정제됨. 액상 형태로 1 mg/mL 농도, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NLRP1 (Accession Q9C000), corresponding to amino acid residues K229–T279 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850146 |
Product Specific Information
Antibody detects endogenous levels of total NLRP1.
Target Information
NALP1 is a member of the Ced-4 family of apoptosis proteins. Members of this family contain a caspase recruitment domain (CARD) and are key mediators of programmed cell death.
The encoded protein includes a distinct N-terminal pyrin-like motif, possibly involved in protein-protein interactions. It interacts strongly with caspase 2 and weakly with caspase 9.
Overexpression of this gene induces apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified, though the biological validity of some variants remains uncertain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명 예시: PA5-100640_NALP1_Q9C000-1_Rabbit_PDP.jpeg)
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