Thermo Fisher Scientific PIG3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:10,000

Product Specifications

Product Specific Information

• Recommended positive control: A549
• Predicted reactivity: Rhesus Monkey (97%), Bovine (89%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The protein encoded by this gene is similar to oxidoreductases, enzymes involved in cellular responses to oxidative stresses and irradiation.
This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death.
It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence.
P53 transcriptionally activates this gene by interacting with the downstream microsatellite sequence, which is polymorphic and may influence cancer susceptibility.
At least two transcript variants encoding the same protein have been identified.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.