Thermo Fisher Scientific GRPR Polyclonal Antibody
GRPR 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용 가능.
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Thermo Fisher Scientific GRPR Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunohistochemistry (IHC) | 1:200–1:2,000 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human GRPR conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: GRPR.
Target Information
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. It is also a potent mitogen for neoplastic tissues.
The effects of GRP are mediated through the gastrin-releasing peptide receptor (GRPR), a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway.
GRPR is aberrantly expressed in various cancers such as lung, colon, and prostate. A balanced translocation between chromosome 8 and chromosome X within the GRPR gene has been observed in an individual with autism and multiple exostoses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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