Thermo Fisher Scientific SUMO-2/3 Monoclonal Antibody (SPM572)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Assay-dependent

Immunohistochemistry (PFA fixed) (IHC (PFA))

• 2–4 µg/mL

Immunocytochemistry (ICC/IF)

• 2–4 µg/mL

Product Specifications

Target Information

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions similarly to ubiquitin, binding to target proteins as part of a post-translational modification system. Unlike ubiquitin, which targets proteins for degradation, SUMO proteins are involved in various cellular processes such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. The protein becomes active after the last two amino acids of the carboxy-terminus are cleaved off. Numerous pseudogenes have been reported, and alternate splice variants encoding different isoforms have been characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.