Thermo Fisher Scientific CTDSP1 Polyclonal Antibody, Biotin
CTDSP1 단백질을 인식하는 Biotin 결합 goat polyclonal antibody로, Human 및 Mouse 시료에 반응합니다. Western blot과 IHC에 사용 가능하며, 모든 CTDSP1 isoform을 인식합니다. 안정적인 액상 형태로 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence EAKAQDSDKIC (aa 82–92) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932817 |
Product Specific Information
- Expected to recognize all three reported isoforms (NP_067021.1; NP_872580.1; NP_001193807.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
CTDSP1 is a class 2C phosphatase with activity dependent on the conserved DxD motif. Expression of CTDSP1 inhibits activated transcription from several promoter-reporter constructs, while phosphatase-inactive mutants enhance transcription. REST/NRSF complex recruits SCPs to neuronal genes containing RE1 elements, leading to silencing in nonneuronal cells. SCP activity is an evolutionarily conserved transcriptional regulator that globally represses neuronal genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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