Thermo Fisher Scientific Dicer Polyclonal Antibody
Dicer 단백질을 인식하는 염소 폴리클로날 항체로, 인간 시료에 반응합니다. IHC(P)에서 3–6 µg/mL 농도로 사용 가능하며, 0.5 mg/mL 농도의 액상 형태로 제공됩니다. RNA 간섭 연구 및 miRNA 경로 분석에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–6 µg/mL |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:2,000.
Product Specifications
| Category | Specification |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence QDKSNTDKWEKDEMTKDC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932823 |
Target Information
Dicer is a double-stranded RNA (dsRNA) endoribonuclease that plays a central role in short dsRNA-mediated post-transcriptional gene silencing. It cleaves long dsRNAs and pre-microRNAs (miRNA) into fragments of 21–23 nucleotides with 3′ overhangs, producing short interfering RNAs (siRNA) and mature microRNAs. These RNA fragments guide the RNA-induced silencing complex (RISC) to complementary RNAs for degradation or translational repression.
RNA interference (RNAi) mediated by siRNAs regulates the elimination of transcripts from repetitive DNA elements and the degradation of exogenous viral RNA. The miRNA pathway specifically controls gene expression at the post-transcriptional level.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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