Thermo Fisher Scientific BCL2L1 Monoclonal Antibody (S1)
인간 BCL2L1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 1:500~1:1,000 희석 비율로 사용 가능. BCL-2 패밀리 단백질 연구에 적합하며, 액상 형태로 제공되고 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S1 |
| Immunogen | BCL2L1 (AAH19307.1, 1–233 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSQSNRELVV DFLSYKLSQK GYSWSQFSDV EENRTEAPEG TESEMETPSA INGNPSWHLA DSPAVNGATG HSSSLDAREV IPMAAVKQAL REAGDEFELR YRRAFSDLTS QLHITPGTAY QSFEQVVNEL FRDGVNWGRI VAFFSFGGAL CVESVDKEMQ VLVSRIAAWM ATYLNDHLEP WIQENGGWDT FVELYGNNAA AESRKGQERF NRWFLTGMTV AGVVLLGSLF SRK
Target Information
The protein encoded by the BCL-X gene belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular processes.
These proteins are located at the outer mitochondrial membrane and regulate VDAC opening, which controls mitochondrial membrane potential, reactive oxygen species production, and cytochrome C release—key factors in apoptosis.
Alternative splicing produces multiple transcript variants encoding two isoforms:
- Long isoform: Apoptotic inhibitor
- Short isoform: Apoptotic activator
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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