Thermo Fisher Scientific TNFRSF17 Monoclonal Antibody (8B4)
인간 TNFRSF17 단백질을 인식하는 Mouse IgG2a 단일클론 항체. Western blot과 ELISA에 적합하며, PBS 기반 보존액에 무보존제 상태로 제공. B세포 발달과 신호전달 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, lambda |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8B4 |
| Immunogen | TNFRSF17 (AAH58291.1, 5–50 a.a.) partial recombinant protein with mouse IgG2a-Fc tag |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVK
Target Information
The protein encoded by this gene is a member of the TNF-receptor superfamily.
This receptor is preferentially expressed in mature B lymphocytes and may be important for B cell development and autoimmune response.
It specifically binds to TNFSF13B/TALL-1/BAFF, leading to NF-kappaB and MAPK8/JNK activation.
It also binds to various TRAF family members, transducing signals for cell survival and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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