Thermo Fisher Scientific CaV1.2 Polyclonal Antibody
CaV1.2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, IHC, ICC/IF, Flow Cytometry, Dot blot 등 다양한 응용에 적합합니다. 인간 및 생쥐에 반응하며, 고순도 정제 및 안정적인 PBS 기반 보존 용액으로 제공됩니다.
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Thermo Fisher Scientific CaV1.2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:50–1:100 |
| Dot blot (DB) | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within mouse CACNA1C aa 802–851 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2854709 |
Product Specific Information
Positive Control: SKOV-3, rat brain tissue, human kidney tissue, human uterus tissue, mouse heart tissue.
Target Information
CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel complex includes alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Multiple isoforms exist, generated by different genes or alternative splicing. The CACNA1C protein binds to and is inhibited by dihydropyridine. Alternative splicing results in various transcript variants encoding distinct proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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