Thermo Fisher Scientific TOM70 Recombinant Rabbit Monoclonal Antibody (6H6F2)
TOM70 단백질을 검출하기 위한 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간, 생쥐, 랫트에 반응하며 HEK293 세포에서 발현된 재조합 항체입니다. 단백질 A로 정제되었으며, 안정적인 액상 형태로 공급됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6H6F2 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 245–608 of human TOM70 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
KNREPLMPSP QFIKSYFSSF TDDIISQPML KGEKSDEDKD KEGEALEVKE NSGYLKAKQY MEEENYDKII SECSKEIDAE GKYMAEALLL RATFYLLIGN ANAAKPDLDK VISLKEANVK LRANALIKRG SMYMQQQQPL LSTQDFNMAA DIDPQNADVY HHRGQLKILL DQVEEAVADF DECIRLRPES ALAQAQKCFA LYRQAYTGNN SSQIQAAMKG FEEVIKKFPR CAEGYALYAQ ALTDQQQFGK ADEMYDKCID LEPDNATTYV HKGLLQLQWK QDLDRGLELI SKAIEIDNKC DFAYETMGTI EVQRGNMEKA IDMFNKAINL AKSEMEMAHL YSLCDAAHAQ TEVAKKYGLK PPTL
Target Information
Functional mitochondria require up to 1000 proteins to function properly, with 99% synthesized as precursors in the cytoplasm and transported into the mitochondria with the aid of cytosolic chaperones and mitochondrial translocators. Proteins to be imported are guided by cytosolic heat shock protein (cHSP70) and interact with Translocators of the Outer Membrane (TOMs) and subsequently with Translocators of the Inner Membrane (TIMs).
TOMM70A is ubiquitously expressed in human tissues and localizes to mitochondria, playing a significant role in the import of nuclear-encoded mitochondrial proteins with internal targeting sites such as ADP/ATP carriers and uncoupling proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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