Thermo Fisher Scientific LMAN1 Polyclonal Antibody
LMAN1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, 인간 단백질에 반응. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Lectin, Mannose Binding 1 (amino acids 198–475 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.64 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903748 |
Target Information
The LMAN1 protein is a type I integral membrane protein localized between the endoplasmic reticulum and the Golgi apparatus, recycling between these compartments. It functions as a mannose-specific lectin and belongs to a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in this gene are associated with a coagulation defect and have been identified as the cause of combined factor V–factor VIII deficiency, a rare autosomal recessive disorder characterized by reduced levels of both coagulation factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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