Thermo Fisher Scientific TRPC3 Polyclonal Antibody
TRPC3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 인간 시료 반응성이 있으며, 4°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 275 to 325 of Human Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
The mammalian transient receptor potential (TRP) superfamily can be divided into three major families, including the canonical TRP (TRPC) family. The seven members of this family share activation through PLC-coupled receptors and are suggested to be components of receptor-regulated cation channels in various cell types.
Members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, indicating a possible mechanism of activation via PLC-coupled receptors.
TRPC3 encodes a Ca²⁺-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. It physically interacts with TRPC6 and TRPC7 to form functional tetrameric channels.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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