Thermo Fisher Scientific Bcl-6 Monoclonal Antibody (BCL6, 1718)
Thermo Fisher Scientific의 Bcl-6 단클론 항체(BCL6, 1718)는 인간 시료에 반응하며 IHC 및 Peptide Array에 사용 가능합니다. Recombinant Bcl-6 단백질을 면역원으로 하며, 고순도 Protein A/G 정제 항체입니다. 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BCL6, 1718 |
| Immunogen | Recombinant human Bcl-6 protein fragment (aa256–389) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature (RT).
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at RT for 20 min.
Target Information
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas.
Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas, and rearrangements have been detected in 33–45% of diffuse large B cell lymphomas.
Immunohistochemical detection of Bcl-6 has been reported in follicular lymphomas, diffuse large B cell lymphomas, Burkitt’s lymphomas, and nodular lymphocyte predominant Hodgkin’s disease.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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