Thermo Fisher Scientific RNASET2 Polyclonal Antibody
Thermo Fisher Scientific의 RNASET2 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하며 Western blot 및 ICC/IF에 사용됩니다. 항원 친화 크로마토그래피로 정제되었고, PBS 버퍼에 0.02% sodium azide가 포함되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid synthetic peptide near the carboxy terminus of human RNASET2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551698 |
Product Specific Information
- A suggested positive control is SW480 cell lysate.
- PA5-34346 can be used with blocking peptide PEP-1389.
Target Information
RNASET2 is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases.
It is a single copy gene mapping to 6q27, a region associated with human malignancies and chromosomal rearrangements, and has been suggested to function as a tumor suppressor protein.
Its expression is suppressed in HTLV-1 infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter.
As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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