Thermo Fisher Scientific APBB1 Monoclonal Antibody (OTI7E3), TrueMAB
인간 APBB1 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합. TrueMAB 포맷으로 고순도 정제되어 있으며 PBS/BSA/glycerol 버퍼에 보존. Alzheimer’s 관련 연구에 활용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7E3 |
| Immunogen | Full length human recombinant protein of human APBB1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer’s disease amyloid precursor protein, transcription factor CP2/LSF/LBP1, and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product’s nuclear translocation. This encoded protein may play an important role in the pathogenesis of Alzheimer’s disease and is thought to regulate transcription. It has been observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene, though some full-length sequences are not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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