Thermo Fisher Scientific Zika Virus NS1 (strain Zika SPH2015) Monoclonal Antibody (15)
Zika virus NS1 단백질을 인식하는 Mouse monoclonal antibody로, Western blot과 ELISA에 적합합니다. 보존제가 포함되지 않아 sodium azide 첨가를 권장하며, 고순도의 Protein A 정제 항체입니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| ELISA | 1:1,000–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 15 |
| Immunogen | Recombinant Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS1 Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785803 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS1.
Target Information
Zika virus (ZIKV), a member of the Flaviviridae family, has a single positive-sense RNA genome initially translated as a polyprotein, which is cleaved into three structural proteins (C, PrM/M, E) and seven nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5).
The glycosylated NS1 forms a homodimer inside cells and is required for viral replication. Later in infection, NS1 is secreted as a hexameric lipoprotein particle that assists immune evasion and pathogenesis by interacting with host immune components.
References:
- Song, H.; Qi, J.; Haywood, J.; Shi, Y.; Gao, G.F. (2016). Nat. Struct. Mol. Biol. 23, 456–458.
- Suthar, M.S., Diamond, M.S. & Gale, M. Jr. (2013). Nat. Rev. Microbiol. 11, 115–128.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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