Thermo Fisher Scientific LGR7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human RXFP1(Accession Q9HBX9), corresponding to amino acid residues R527-Q577. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LGR7,uniProtId:Q9HBX9-1,ncbiNodeId:9606,antigenRange:527-577,antigenLength:757,antigenImageFileName:PA5-99926_LGR7_Q9HBX9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99926_LGR7_Q9HBX9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2818859

Product Specific Information

Antibody detects endogenous levels of total RXFP1.

Target Information

LGR7 is a low density lipoprotein receptor of 757amino acid belonging to the G-protein coupled receptor 1 family with rhodopsin-like receptor activity. It has seven transmembrane region, cysteine-rich motif, 10 LRR domains and 5 N-glycosylation sites in the N terminus. Research reports show that it has receptor for relaxins (RLN1 and RLN2) which stimulates adenylate cyclase activation, substrate adhesion, and chemo migratory capacity of mononuclear leukocytes. LGR7 is critical for mediating these biological responses by use of RNA interference lentiviral short hairpin constructs. It is widely expressed in 86% of 15 primary EC tissue samples including brain, kidney, testis and endometrium.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.