Thermo Fisher Scientific BIRC3 Monoclonal Antibody (OTI3G4), TrueMAB
BIRC3 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 Flow cytometry에 적합. Human 시료 반응성. Lyophilized 형태, PBS buffer에 8% trehalose 포함. 재구성 후 1 mg/mL 농도 사용 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 255–529 of human BIRC3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The BIRC3 gene encodes a member of the inhibitor of apoptosis (IAP) family. This protein binds to TRAF1 and TRAF2, likely interfering with activation of ICE-like proteases, thereby inhibiting apoptosis induced by serum deprivation. It does not inhibit apoptosis caused by menadione exposure. The protein includes three baculovirus IAP repeat domains and one RING finger domain. Transcript variants encoding the same isoform have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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