Thermo Fisher Scientific IL-12 p35 Monoclonal Antibody (C3)
IL-12 p35 단일클론 항체(C3)는 인간 IL-12A 단백질을 인식하는 Mouse IgG2b 항체로, Western blot에 적합합니다. 단백질 A/G로 정제되었으며 PBS와 50% glycerol에 보관됩니다. 면역반응 및 사이토카인 연구용으로 활용됩니다.
- 카탈로그번호
- MA541615
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 0.01–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C3 |
| Immunogen | Recombinant protein Interleukin 12A (amino acids 23–219) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899097 |
Target Information
Interleukin 12A (IL-12A) is a signaling cytokine belonging to the Interleukin-6 protein superfamily. It is a 35 kDa subunit of the heterodimeric cytokine IL-12 and exhibits a wide range of biological activities. IL-12A acts as a growth factor for activated T and NK cells, enhances NK/lymphokine-activated killer cell activity, and stimulates IFN-γ production. It contributes to Th1 and Th2 differentiation and regulates tyrosine phosphorylation of Stat4. IL-12A signaling in innate immunity involves nitric oxide synthase 2A. Together with EBI3, IL-12A forms interleukin-35 (IL-35), produced by Treg cells and required for maximal suppressive activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: MA5-41615_IL-12_p35_P29459-1_House_mouse.svg, MA5-41615_IL-12_p35_P29459-1_House_mouse_PDP.jpeg)
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