Thermo Fisher Scientific L2HGDH Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human L2HGDH. Recombinant protein control fragment (Product #RP-104004). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:L2HGDH,uniProtId:Q9H9P8-1,ncbiNodeId:9606,antigenRange:174-250,antigenLength:463,antigenImageFileName:PA5-64221_L2HGDH_Q9H9P8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64221_L2HGDH_Q9H9P8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643241

Product Specific Information

Immunogen sequence: KKEPYCRGLM AIDCPHTGIV DYRQVALSFA QDFQEAGGSV LTNFEVKGIE MAKESPSRSI DGMQYPIVIK NTKGEEI

Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 78%.

Target Information

This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.