Thermo Fisher Scientific Seipin Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:2,000
• Immunocytochemistry (ICC/IF): 1:100–1:500

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total BSCL2.

Target Information

This gene encodes the protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology.
Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 (Berardinelli-Seip syndrome), a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.