Thermo Fisher Scientific NLRC4 Polyclonal Antibody
Human NLRC4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 A 및 B iso폼 모두 검출 가능. 항원 친화 크로마토그래피로 정제된 고순도 항체로, 연구용으로만 사용.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminal sequence: M N F I K D N S R A L I Q R M G M |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at −20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2151982 |
Product Specific Information
PA1-4264 detects CLAN protein from human samples and recognizes both A and B isoforms.
Successfully used in Western blot procedures, detecting a ~116 kDa CLAN-A and a ~43 kDa CLAN-B in lung lysate.
Immunizing peptide corresponds to the N-terminal sequence M N F I K D N S R A L I Q R M G M.
Target Information
NLRC4 encodes a member of the caspase recruitment domain-containing NLR family, which plays essential roles in innate immune responses to pathogenic organisms, tissue damage, and cellular stress.
Mutations in NLRC4 can cause autoinflammation with infantile enterocolitis.
Alternative splicing produces multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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