Thermo Fisher Scientific NLRC4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic Peptide corresponding to the N-terminal sequence M N F I K D N S R A L I Q R M G M if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NLRC4,uniProtId:Q9NPP4-1,ncbiNodeId:9606,antigenRange:1-17,antigenLength:1024,antigenImageFileName:PA1-4264_NLRC4_Q9NPP4-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4264_NLRC4_Q9NPP4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2151982

Product Specific Information

PA1-4264 detects CLAN protein from human samples. This antibody detects both A and B isoforms.

PA1-4264 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~116 kDa protein representing CLAN-A and a ~43 kDa protein representing CLAN-B in lung lysate.

PA1-4264 immunizing peptide corresponds to N-terminal sequence M N F I K D N S R A L I Q R M G M.

Target Information

NLRC4 encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.